Salmonella: A review on pathogenesis, epidemiology and antibiotic resistance

Autor: Nurul Syakima Ab Mutalib, Kok-Gan Chan, Shu Kee Eng, Learn Han Lee, Priyia Pusparajah, Hooi-Leng Ser
Rok vydání: 2015
Předmět:
Zdroj: Frontiers in Life Science. 8:284-293
ISSN: 2155-3777
2155-3769
DOI: 10.1080/21553769.2015.1051243
Popis: Salmonella is one of the most frequently isolated foodborne pathogens. It is a major worldwide public health concern, accounting for 93.8 million foodborne illnesses and 155,000 deaths per year. To date, over 2500 Salmonella serotypes have been identified and more than half of them belong to Salmonella enterica subsp. enterica, which accounts for the majority of Salmonella infections in humans. Salmonella infections that involve invasive serotypes are often life threatening, necessitating appropriate and effective antibiotic therapy. The emergence of multi-drug-resistant (MDR) Salmonella serotypes is having a great impact on the efficacy of antibiotic treatment, and an increasing prevalence of MDR strains may lead to an increase in mortality rates of Salmonella infections. Epidemiological studies indicate that MDR Salmonella serotypes are more virulent than susceptible strains, as reflected by increased severity and more prolonged disease in patients infected by MDR strains. Preventive measures have been ...
Databáze: OpenAIRE