In vitro and in silico anti-leukemic activity of 2-amino-6-nitro-4-(4-oxo-2-thioxothiazolidin-5-yl)-4H-chromene-3-carbonitrile (ANC) through inhibition of anti-apoptotic Bcl-2 proteins

Autor:	Ahana Roy Choudhury, Adhikesavan Harikrishnan, Vijay Veena
Rok vydání:	2021
Předmět:	0303 health sciences Chemistry In silico 030303 biophysics Context (language use) General Medicine In vitro 03 medical and health sciences Biochemistry Structural Biology Apoptosis Nitro Selectivity Molecular Biology
Zdroj:	Journal of Biomolecular Structure and Dynamics. 40:7018-7026
ISSN:	1538-0254 0739-1102
DOI:	10.1080/07391102.2021.1893223
Popis:	An array of 4H-chromene derivatives have been reported for anticancer properties but their selectivity and mode of anticancer activity are unexplored. In this context, we have investigated a biolog...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::306154a74671cd7fb24e78a35c757be9 https://doi.org/10.1080/07391102.2021.1893223 Zobrazit plný text záznamu