The Distribution of Radioactive Potassium in the Uterus of Pregnant Rats and Guinea-pigs
| Autor: | R. J. Harrison, J. L. D'Silva |
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| Rok vydání: | 1953 |
| Předmět: | |
| Zdroj: | Development. 1:357-368 |
| ISSN: | 1477-9129 0950-1991 |
| DOI: | 10.1242/dev.1.4.357 |
| Popis: | The distribution of tracer amounts of 42KC1 was studied in the kidney, placenta, uterus, and foetus (a) 5 minutes to 24 hours after injection into pregnant rats (20-21 days), and (b) 5 minutes after injection into pregnant rats (11-18 days) and guinea-pigs (near term). “ The changes in activity in the kidney and foetus (per gramme of tissue) indicate that the former exchanges its potassium rapidly and the latter slowly. The activity of the labyrinthine placenta of rats near term falls from 0·53 per cent, (per gramme of tissue) of the total injected radioactivity after 5 minutes to 0·29 per cent, after 24 hours. The activity of the uterus changes similarly and suggests a rapid rate of exchange and a slow blood-flow. The radioactivity of the uterus was not significantly different in the nonpregnant uterus, the non-pregnant horn of the pregnant uterus, and the pregnant horn. The placentae in different parts of the horn do not appear to have a significant advantage or disadvantage in regard to the availability of potassium. The amniotic fluid and vascular splanchnopleur contained only small amounts of radioactivity. The labyrinthine placenta was uniformly active throughout. The potassium content of the labyrinthine placenta, pregnant and nonpregnant uterus, has been determined. |
| Databáze: | OpenAIRE |
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