Synthesis and antifungal activity against strains ofcandida albicansof 6-fluoro-4(5 or 7)-chloro-2-(difluorobenzoyl)aminobenzothiazoles

Autor:	Flaviano Morlacchi, Antonio Rosato, Domenico Armenise, Nicolino De Laurentis, Antonia Reho
Rok vydání:	2004
Předmět:	Antifungal Biochemistry biology Chemistry medicine.drug_class Organic Chemistry medicine Biological activity Candida albicans biology.organism_classification In vitro
Zdroj:	Journal of Heterocyclic Chemistry. 41:771-775
ISSN:	1943-5193 0022-152X
DOI:	10.1002/jhet.5570410520
Popis:	A series of 6-fluoro-4-(5 or 7)-chloro-2-(difluorobenzoyl)aminobenzothiazoles 3a-r were prepared to investigate their potential biological activity. In this work, the results of their in vitro antifungal activity against some strains of Candida albicans are reported. It was found that some derivatives displayed antifungal activity higher than that for 3k [1a] compound already described in literature.
Databáze:	OpenAIRE
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