Cushing’s disease presenting with psychosis

Autor:	Nigel Hoggard, Ahmed Saeed Mubarak Mohamed, Ahmed Iqbal, Suveera Prasad, Daniel Blackburn
Rok vydání:	2021
Předmět:	Psychosis Pediatrics medicine.medical_specialty Neurology Metyrapone business.industry General Medicine Cushing's disease Disease medicine.disease medicine Endocrine system Neurology (clinical) Headaches medicine.symptom business Pituitary microadenoma medicine.drug
Zdroj:	Practical Neurology. 21:351-353
ISSN:	1474-7766 1474-7758
DOI:	10.1136/practneurol-2021-002974
Popis:	Cushing’s disease is a rare endocrine condition in which a pituitary corticotroph adenoma drives excess adrenal cortisol production, and is one cause of endogenous Cushing’s syndrome. We present a young woman with 3 weeks of headaches and cognitive disturbance who subsequently developed florid psychosis requiring multiple admissions under neurology and psychiatry. Her clinical stigmata of hypercortisolism and biochemical abnormalities prompted an MR scan of the pituitary, which confirmed a pituitary microadenoma. Treatment with metyrapone and subsequent surgery led to complete recovery within 2 months. Cushing’s disease commonly causes neuropsychiatric symptoms and can present with psychosis. Diagnosing Cushing’s disease can be challenging, but with early diagnosis and treatment it has an excellent prognosis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::3018cebfd5a303b7519be877216fb14e https://doi.org/10.1136/practneurol-2021-002974 Zobrazit plný text záznamu