Leukocytoclastic Vasculitis in Hairy Cell Leukemia (Leukemic Reticuloendotheliosis)
| Autor: | David T. Shum, Marvin S. Smout, Patrick G. W. Kenny |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Pathology
medicine.medical_specialty medicine.diagnostic_test business.industry Polyarteritis nodosa medicine.medical_treatment Splenectomy Spleen Dermatology General Medicine medicine.disease Peripheral blood mononuclear cell medicine.anatomical_structure Skin biopsy medicine Hairy Cell Hairy cell leukemia business Vasculitis |
| Zdroj: | Archives of Dermatology. 119:1018 |
| ISSN: | 0003-987X |
| DOI: | 10.1001/archderm.1983.01650360064015 |
| Popis: | The incidence of skin lesions in hairy cell leukemia is low. In a series of 71 cases, ten patients had cutaneous lesions of an unspecified type and only one patient had a diagnostic infiltration of hairy cells found in the skin biopsy specimen. 1 Recently, polyarteritis nodosa with nodular panniculitis 2 and necrotic skin lesions on the legs with acute neutrophilic vasculitis 3 have been reported in association with hairy cell leukemia. We describe a patient with hairy cell leukemia who had widespread papules and plaques with pustules. Histopathologically, these lesions showed an acute leukocytoclastic vasculitis. Report of a Case In 1978, hairy cell leukemia (leukemic reticuloendotheliosis) was diagnosed in a 46-year-old man. This diagnosis was based on the finding of tartrate-resistant-acid-phosphatase-positive-staining hair cells in peripheral blood smears. He had had a therapeutic splenectomy in 1978. The spleen showed mononuclear cell infiltrates characteristic of leukemic reticuloendotheliosis on histologic examination. A |
| Databáze: | OpenAIRE |
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