Magnetic fluid thermochemotherapy of murine tumors

Autor:	Vycheslav D. Kuznetsov, Elena Yu. Filinova, N. A. Brusentsov, Nikolai Y. Jurchenko, L. I. Shumakov, T. N. Brusentsova
Rok vydání:	2005
Předmět:	Melphalan Ferrofluid Magnetic hyperthermia Nuclear magnetic resonance Life span Chemistry medicine Tumor regression Tumor therapy Dextran Derivatives Condensed Matter Physics Electronic Optical and Magnetic Materials medicine.drug
Zdroj:	Journal of Magnetism and Magnetic Materials. 293:450-454
ISSN:	0304-8853
Popis:	Four series of water-based dextran-ferrite (DF) magnetic fluids (MFs) containing Melphalan (MP) were prepared. Their saturation magnetization ( M s ) was from 0.8 to 7.8 kA/m; specific power absorption rates were 240 W/g Fe. After nine courses of magnetic fluid thermochemotherapy with MP containing DF MF ( M s 7.5 kA/m, pH 6.6, ζ+15 mV) at 44–46 °C for 30 min in an AC magnetic field (0.88 MHz, 9.3 kA/m, 0.3 kW), complete P388 tumor regression was seen in 30% of BDF 1 mice. Furthermore, a life span increase of 180% was achieved.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2ff32b18f0464589a40243bb9e636805 https://doi.org/10.1016/j.jmmm.2005.02.039 Zobrazit plný text záznamu Full Text from ScienceDirect