Case report of Zika virus during controlled ovarian hyperstimulation: results from follicular fluid, cumulus cells and oocytes
Autor: | Mariana Angelozzi de Oliveira, Leonardo Previato Araújo, Ligiane A. Machado-Paula, Cassio L. Facio, Ciro Dresch Martinhago, Edilberto De Araújo Filho, Lígia Fernanda P Araújo |
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Rok vydání: | 2019 |
Předmět: |
0301 basic medicine
endocrine system Oocyte Aspiration In vitro fertilisation biology urogenital system business.industry medicine.medical_treatment 030231 tropical medicine Semen Controlled ovarian hyperstimulation biology.organism_classification Rash Follicular fluid Zika virus Andrology 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Real-time polymerase chain reaction medicine medicine.symptom business |
Zdroj: | JBRA Assisted Reproduction. |
ISSN: | 1518-0557 |
DOI: | 10.5935/1518-0557.20180081 |
Popis: | We describe a case of a 37-year-old female, indicated for in vitro fertilisation. She developed skin rash on her trunk and limbs, during the treatment. RT-PCR results were positive in her blood and negative in her husband's blood and semen. Oocyte aspiration was performed, retrieving 7 oocytes, follicular fluid, and cumulus cells. RT-PCR results for the follicular fluid and cumulus cells were negative for ZIKV, and positive for only 2 oocytes. This is the first report in the literature analysing ZIKV in the follicular fluid, cumulus cells, and oocytes, and will contribute to the understanding of ZIKV infection and transmission. |
Databáze: | OpenAIRE |
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