Case report of Zika virus during controlled ovarian hyperstimulation: results from follicular fluid, cumulus cells and oocytes

Autor: Mariana Angelozzi de Oliveira, Leonardo Previato Araújo, Ligiane A. Machado-Paula, Cassio L. Facio, Ciro Dresch Martinhago, Edilberto De Araújo Filho, Lígia Fernanda P Araújo
Rok vydání: 2019
Předmět:
Zdroj: JBRA Assisted Reproduction.
ISSN: 1518-0557
DOI: 10.5935/1518-0557.20180081
Popis: We describe a case of a 37-year-old female, indicated for in vitro fertilisation. She developed skin rash on her trunk and limbs, during the treatment. RT-PCR results were positive in her blood and negative in her husband's blood and semen. Oocyte aspiration was performed, retrieving 7 oocytes, follicular fluid, and cumulus cells. RT-PCR results for the follicular fluid and cumulus cells were negative for ZIKV, and positive for only 2 oocytes. This is the first report in the literature analysing ZIKV in the follicular fluid, cumulus cells, and oocytes, and will contribute to the understanding of ZIKV infection and transmission.
Databáze: OpenAIRE