| Popis: |
Older individuals appear to be relatively resilient to cognitive impairment when sleep deprived. Several explanations have been proposed, including bias towards preserving performance accuracy at the cost of speed, reduced amplitude of circadian rhythm, and slower build-up of sleep pressure during wakefulness. These aging effects are overshadowed by individual differences in performance impairment due to sleep loss that are unrelated to age. Such individual differences are stable and robust, constituting a phenotype. Baseline brain activation levels and some gene polymorphisms predict this phenotype to some extent, but much of the variability in resilience to impairment from sleep deprivation remains unexplained. |
