Prognostic Significance of Glycoprotein 96 in Human Hepatocellular Carcinoma

Autor: Jing Gang Fang, Bing Xu, Xiaoping Wang, Ke Pei Zhang, Yi Xin Yang, Huan Ping Lin
Rok vydání: 2014
Předmět:
Zdroj: Advanced Materials Research. :1037-1040
ISSN: 1662-8985
DOI: 10.4028/www.scientific.net/amr.989-994.1037
Popis: Glycoprotein 96(gp96) is highly expressed in cancer tissues. Recent studies indicate the possible roles of gp96 in the development and progression of hepatocellular carcinomas but detailed information is still ambiguous. The aim of the study is to investigate the correlation between clinicopathology and immunolocalization of gp96 in human hepatocellular carcinoma. Immunohistochemistry demonstrated that gp96 expression in hepatocellular carcinomas with metastasis was significantly higher than those with non-metastasis. Gp96 expression was significantly associated with the presence of tumor infiltration, lymph node and remote metastasis.
Databáze: OpenAIRE