A compact fluorescence/circular dichroism dual-modality probe for detection, differentiation, and detoxification of multiple heavy metal ions via bond-cleavage cascade reactions
| Autor: | Chao Song, Feng Gao, Huijuan Ma, Na Wang, Wei Wang, Junwei Chen, Hongjuan Tong, Yajun Zhang, Huan Xu, Kaiyan Lou |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Circular dichroism
Chemistry Metal ions in aqueous solution Imine 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology Photochemistry Cleavage (embryo) 01 natural sciences Fluorescence 0104 chemical sciences Metal Hydrolysis chemistry.chemical_compound visual_art visual_art.visual_art_medium 0210 nano-technology Bond cleavage |
| Zdroj: | Chinese Chemical Letters. 32:3876-3881 |
| ISSN: | 1001-8417 |
| Popis: | Selective detection of multiple analytes in a compact design with dual-modality and theranostic features presents great challenges. Herein, we wish to report a coumarin-thiazolidine masked D -penicillamine based dual-modality fluorescent probe COU-DPA-1 for selective detection, differentiation, and detoxification of multiple heavy metal ions (Ag+, Hg2+, Cu2+). The probe shows divergent fluorescence (FL) /circular dichroism (CD) responses via divergent bond-cleavage cascade reactions (metal ion promoted C-S cleavage and hydrolysis at two distinctive cleavage sites): FL “turn-off” and CD “turn-on” for Ag+ (no hydrolysis), FL “turn-on” and CD “turn-off” for Hg2+ (imine hydrolysis), and FL “self-threshold ratiometric” and CD “turn-off” for excess Cu2+ (lactone and imine hydrolysis), providing the first example of a fluorescence/CD dual-modality probe for multiple species with complimentary responses. Moreover, the bond-cleavage cascade reactions also lead to the formation of D -penicillamine heavy metal ion complexes for potential detoxification treatments. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect