Process Safety Considerations for the Supply of a High-Energy Oxadiazole IDO1-Selective Inhibitor

Autor:	Josep Saurí, Michael J. Ardolino, Zhiguo J. Song, Lu Chen, Daniel J. Muzzio, Lushi Tan, Thomas Vickery, Jingjun Yin, Ji Qi, Chaomin Li, Yu-hong Lam, Ralph Zhao, Theodore A. Martinot, Matthew L. Maddess
Rok vydání:	2019
Předmět:	chemistry.chemical_compound Materials science chemistry Process safety 010405 organic chemistry Organic Chemistry Oxadiazole Physical and Theoretical Chemistry 010402 general chemistry 01 natural sciences Combinatorial chemistry 0104 chemical sciences
Zdroj:	Organic Process Research & Development. 23:1178-1190
ISSN:	1520-586X 1083-6160
DOI:	10.1021/acs.oprd.9b00105
Popis:	The development of a stereospecific synthesis of a IDO1-selective inhibitor is described. The synthetic strategy toward enabling early discovery efforts along with additional findings pertaining to...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2fa9f7077763e03ea8e46e168c12e2d5 https://doi.org/10.1021/acs.oprd.9b00105 Zobrazit plný text záznamu