Engineered nanoporous gold microspheres for stochastic sensing

Autor:	Carmen Cristina Surdu-Bob, Raluca-Ioana Stefan-van Staden, Iuliana Moldoveanu, Camelia Stanciu-Gavan
Rok vydání:	2014
Předmět:	Detection limit Analyte Materials science Screening test biology Nanoporous General Chemical Engineering New materials Nanotechnology General Chemistry Microsphere Carcinoembryonic antigen Gold particles biology.protein
Zdroj:	RSC Adv.. 4:54140-54143
ISSN:	2046-2069
DOI:	10.1039/c4ra08987a
Popis:	Engineered nanoporous gold microspheres were designed and used as new materials for stochastic microsensors. Carcinoembryonic antigen was used as model analyte to prove the stochastic sensing capabilities of the new material. A new sensor based on gold particles was used for the assay of the carcinoembryonic antigen in biological fluids. Stochastic sensing was used to determine the antigen in the samples. The working concentration range of the stochastic microsensor (1.6 × 10−8 to 1.6 × 10−5 mg mL−1) as well as its sensitivity (3.0 × 103 s mg mL−1) and limit of quantification (16 ng mL−1) made possible its reliable utilization for screening tests of whole blood samples for the carcinoembryonic antigen.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2f998e4fd880bcc11ece1f336bc66c4a https://doi.org/10.1039/c4ra08987a Zobrazit plný text záznamu