Blood vessel invasion and axillary lymph node involvement as prognostic indicators for human breast cancer

Autor:	Ray A. Weigand, Jose Russo, Michael J. Brennan, Marvin A. Rich, William M. Isenberg
Rok vydání:	1982
Předmět:	Oncology Cancer Research medicine.medical_specialty Tumor size business.industry Incidence (epidemiology) Cancer Axillary Lymph Node Involvement medicine.disease medicine.anatomical_structure Breast cancer Internal medicine medicine Stage (cooking) business Human breast Blood vessel
Zdroj:	Cancer. 50:962-969
ISSN:	1097-0142 0008-543X
Popis:	Blood vessel invasion and axillary lymph node involvement were examined in 175 breast cancer patients. The incidence of blood vessel invasion was 35%. The presence of blood vessel invasion was highly associated with early disease recurrence. The association of poor prognosis with blood vessel invasion was independent of clinical stage, menopausal status, node status, tumor size, or postsurgical treatment. Those patients with blood vessel invasion and two or more positive nodes were at extremely high risk for early recurrence (70% recurrence by two years compared with 15% recurrence in the remainder of the patients). Thus, blood vessel invasion is a useful indicator of early recurrence in patients with primary breast cancer and, in combination with node status, is a prognostic indicator with high discriminatory power.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2f8756969cdb955e4bc5bcc0309131c6 https://doi.org/10.1002/1097-0142(19820901)50:5<962::aid-cncr2820500526>3.0.co Zobrazit plný text záznamu Plný text