Antibiogram and Multiple Antibiotics Resistance Indices of Bacterial Isolates from Urine of Diabetics and Nondiabetics Attending Some Hospitals in Rivers State, Nigeria

Autor: Hanson, Asikiya Huldah, Akani, Nedie Patience, Williams, Janet Olufunmilayo, Sampson, Tonye
Rok vydání: 2023
Předmět:
Zdroj: Journal of Advances in Microbiology. 23:19-26
ISSN: 2456-7116
DOI: 10.9734/jamb/2023/v23i2706
Popis: There is an increase in the number of cases of antimicrobial resistance with a paucity of data from developing nations. This study is aimed at determining the antibiograms of uropathogens isolated from diabetics and non-diabetic subjects in three hospitals in Rivers State Port Harcourt, Nigeria. The Kirby-Bauer disc diffusion procedure was used to determine the antimicrobial susceptibility pattern of the uropathogens with the following antibiotics: vancomycin, cefotaxime, cefuroxime, imipenem, cefoxitin, ceftazidime, erythromycin, ciprofloxacin, tetracycline, amoxiclav and ofloxacin. The results show that S. aureus (20%), E. coli (9%), K. aerogenes (8%), and K. ascobata (7%) were the most prevalent bacterial isolates. Data showed the isolates were sensitive to imipenem (18.6%), ofloxacin (13.8%) and ceftazidime (12.3%). On the other hand, the antibiotics with the highest resistance were cefotaxime (9.5%), tetracycline (14.1%), erythromycin (18.4%), and vancomycin (21.1%). The diabetic subjects showed a significantly (P < 0.0001) lower prevalence of bacteria with MAR indices below 0.2 but a significantly (P =
Databáze: OpenAIRE