N-azirin-3-yl and N-indol-3-yl azaxylylenes

Autor:	Richard C. Storr, K.R. Randles, Colin W. G. Fishwick, P.W. Manley
Rok vydání:	1985
Předmět:	chemistry.chemical_compound Bicyclic molecule Nitrile Chemistry Organic Chemistry Drug Discovery Sous vide Organic chemistry Nuclear magnetic resonance spectroscopy Methylene Biochemistry Medicinal chemistry Pyrolysis
Zdroj:	Tetrahedron Letters. 26:3053-3056
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)98616-7
Popis:	Flash-vacuum pyrolysis of N-(2,3-diphenylazirin-3-yl)dihydrobenzoxainones leads to transient N-azirinyl- and N-indolylazaxylylenes which give 2-arylindoles (5) and dihydroindoloquinolines (8) respectively. 5H-1,4-Benzodiazepines are implicated as the precursors to the indoles via the methylene nitrile ylides (9) and an alternative route to the latter by flash pyrolysis of N-(2-methylphenyl)benzimidoyl chlorides (10) provides a new, simple route to 2-arylindoles.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2f5d6fb8b850b6c85bea07f0e1bef4e9 https://doi.org/10.1016/s0040-4039(00)98616-7 Zobrazit plný text záznamu