Présentation inhabituelle d’une granulomatose de Wegener

Autor: Fatma Boussema, Ouahida Cherif, S. Ketari Jamoussi, E. Turki, L. Rokbani, Samir Kochbati, B. Ben Dhaou, M. Maamar
Rok vydání: 2010
Předmět:
Zdroj: La Revue de Médecine Interne. 31:e16-e18
ISSN: 0248-8663
Popis: We report an unusual case of Wegener's granulomatosis revealed by spleen infarction and complicated by reno-vascular hypertension. A 33-year-old man with a history of spleen infraction and cerebral venous thrombosis was admitted for malignant hypertension, renal failure and nephritic syndrome. On Doppler renal ultrasonography, ostial stenosis of the right renal artery was evidenced. Right kidney was non functional on scintigraphy and the patient underwent a right nephrectomy. Granulomatous vasculitis of the right renal artery was found but anti-neutrophilic cytoplasmic antibodies were absent. The diagnosis of Wegener's granulomatosis was suspected. The patient was treated with cyclophosphamide, corticosteroids and plasma exchanges, and renal function markedly improved.
Databáze: OpenAIRE