A phase I/II study of nedaplatin and 5-fluorouracil with concurrent radiotherapy in patients with T4 esophageal cancer: Japan Clinical Oncology Group trial (JCOG 9908)
| Autor: | Narikazu Boku, Yoshikazu Kagami, Keiji Nihei, Shigeaki Yoshida, Yoshinori Ito, Atsushi Ohtsu, Satoshi Ishikura, Kiyomi Mera, Kuniaki Shirao, Kei Muro |
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| Rok vydání: | 2005 |
| Předmět: |
Oncology
Cisplatin medicine.medical_specialty business.industry medicine.medical_treatment Gastroenterology Phases of clinical research Esophageal cancer medicine.disease Clinical trial Radiation therapy chemistry.chemical_compound chemistry Fluorouracil Surgical oncology Internal medicine medicine Nedaplatin business medicine.drug |
| Zdroj: | Esophagus. 2:133-137 |
| ISSN: | 1612-9067 1612-9059 |
| DOI: | 10.1007/s10388-005-0055-3 |
| Popis: | Background Nedaplatin is an analogue of cisplatin with less nonhematologic toxicity. The combination of nedaplatin and 5-fluorouracil showed a promising response rate in a previous phase II study for metastatic esophageal cancer. The purpose of this study was to determine a recommended dose and to evaluate the efficacy of nedaplatin and 5-fluorouracil combined with concurrent radiotherapy. |
| Databáze: | OpenAIRE |
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