The daily costs of chemotherapy-associated adverse events: A cluster-based analysis
| Autor: | S. J. Ross, Kevin Fox, M. H. Weiner, Jeffrey H. Silber, Orit Even-Shoshan, J. I. Mathew |
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| Rok vydání: | 2005 |
| Předmět: | |
| Zdroj: | Journal of Clinical Oncology. 23:6001-6001 |
| ISSN: | 1527-7755 0732-183X |
| DOI: | 10.1200/jco.2005.23.16_suppl.6001 |
| Popis: | 6001 Background: Chemotherapy-associated adverse events (C-AEs) including neutropenia (N), anemia (A), thrombocytopenia (T), mucositis (M) and dehydration (D) are common and associated with increased hospital costs. However, C-AEs often occur in clusters, and as a consequence, it makes little clinical sense to discuss the costs associated with a single C-AE in isolation from other C-AEs. Methods: This study estimates the costs of inpatient and outpatient C-AEs based on a new approach to classifying C-AEs - the clinically relevant C-AE cluster. The study population included all cancer patients receiving chemotherapy (N=2,067) during August 1, 2000 and July 31, 2001 at The University of Pennsylvania Health System. For these patients, C-AE clusters were determined using clinical algorithms based on the start and end dates of defined adverse events and dates of chemotherapy administration. Regression models were developed using a loglinear variance adjusted estimation procedure, to better estimate the daily c... |
| Databáze: | OpenAIRE |
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