Simultaneous Assessment of Cerebral Oxygenation and Hemodynamics During a Motor Task

Autor: Arno Villringer, José M. Valdueza, Ulrich Dirnagl, Christina Hirth, Hellmuth Obrig
Rok vydání: 1997
Předmět:
Zdroj: Advances in Experimental Medicine and Biology ISBN: 9781461376897
Popis: During performance of a sequential finger opposition task we measured changes in regional cerebral blood oxygenation (rCBO) over the motor cortex and blood flow velocity changes (CBFV) in the middle cerebral artery in a combined near-infrared spectroscopy (NIRS) and transcranial Doppler Sonography (TCD) study. Stimulus duration was 60 s followed by a 90 s rest period. During performance of the motor task we observed an increase in [oxy-Hb] a decrease in [deoxy-Hb] and an increase in MCA flow velocity. These changes were significantly more pronounced contralaterally than ipsilaterally to the moving hand. The time course of changes in [oxy-Hb] and CBFV were strikingly similar, showing a pronounced initial over-shoot.
Databáze: OpenAIRE