Seroprevalence and risk factors associated with anti-Toxoplasma gondii antibodies in pregnant women attending antenatal clinics in Benue state, Nigeria

Autor:	Damer P. Blake, Idris A. Lawal, Junaidu Kabir, Ifeoma Nancy Obijiaku, Jacob K. P. Kwaga
Rok vydání:	2019
Předmět:	Antenatal clinics medicine.medical_specialty biology Obstetrics business.industry biology.protein medicine Toxoplasma gondii Seroprevalence Antibody biology.organism_classification business
Zdroj:	International Journal of Research in Medical Sciences. 7:3280
ISSN:	2320-6012 2320-6071
DOI:	10.18203/2320-6012.ijrms20193654
Popis:	Background: Toxoplasmosis causes serious economic losses in livestock. Congenital transmission can occur in pregnant women, commonly with serious consequences.Methods: A cross-sectional study was designed to screen for the absence or presence of anti-T. gondii IgM or IgG antibodies and explore associated risk factors in pregnant women (n=261) that attended antenatal clinics in selected hospitals in Benue state, Nigeria. Blood samples were subjected to enzyme linked immunosorbent assay (ELISA). Information on sociodemographic data and possible risk factors were obtained using a structured questionnaire.Results: Out of 261 pregnant women, 19 (7.3%) and 108 (41.1%) were seropositive for anti-T. gondii IgM and IgG respectively. Comparison of IgM and IgG results suggested that 4.4% presented evidence of possible primary infection, 38.7% previous exposure, 2.8% possible reactivated or chronic infections and 51.8% were susceptible to T. gondii infection. The nature of women’s housing was significantly associated with anti-T. gondii IgM seropositivity (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2ef03945ee766aa9a9798266220b3811 https://doi.org/10.18203/2320-6012.ijrms20193654 Zobrazit plný text záznamu