| Autor: |
Neha Singh, Nilotpal Chowdhury, Shalinee Rao, Shruti Agrawal, Sanjeev Kishore, Vinay Nagaraja Gowda, Rekha Bhandari, Arvind Kumar Gupta, Harish Chandra, Amit Gupta |
| Rok vydání: |
2020 |
| Předmět: |
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| DOI: |
10.1101/2020.12.16.20248306 |
| Popis: |
BackgroundBone marrow metastasis is a significant presentation of many non-hematological malignancies. The present study was conducted with the aim of analysing the clinical, hematological and biochemical parameters of the patients with bone marrow metastases and to determine the parameters which could be possible indicators of bone marrow metastases.Material and methodsBone marrow aspirate, imprint and biopsy slides of 22 cases with bone marrow metastases were reviewed and the hematological and biochemical data of all these cases was compared with that of 20 controls who had no evidence of metastases.ResultsThe mean values of mean platelet volume (MPV), neutrophil to lymphocyte ratio (NLR) and serum lactate dehydrogenase (LDH) were found to be significantly different (p3.5 and LDH>452 U/L showed high likelihood ratio in predicting bone marrow metastases.ConclusionParameters such as MPV, NLR and LDH can be used as efficient and easily available means to predict bone marrow metastasis for an early diagnosis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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