Pulmonary Arteriovenous Malformation in the Korean Population: Clinical Manifestations and the Long-Term Results of Transarterial Embolotherapy

Autor: Jae A Lee, Byung Suk Roh, Hyo Sung Kwak, Gong Young Jin, Young Min Han
Rok vydání: 2010
Předmět:
Zdroj: Journal of the Korean Society of Radiology. 63:495
ISSN: 2288-2928
1738-2637
DOI: 10.3348/jksr.2010.63.6.495
Popis: Purpose: This study was designed to evaluate the general features and the long-term results of transarterial embolotherapy (TAE) for the treatment of pulmonary arteriovenous malformations (PAVMs). Materials and Methods: Thirteen (n=13) patients who underwent TAE for PAVMs were identified. These patients were comprised of 4 men and 9 women, aged between 19 and 67 years (mean age, 44 years). The authors evaluated the general features of PAVMs, including, type, location, size, and symptoms. In addition, results following TAE were analyzed to evaluate its efficacy, and to investigate arterial oxygen pressure changes. Results: In total, 13 patients presented with 21 angiographically confirmed PAVMs. Nine (69.2%) patients had single PAVM. Of the 21 PAVMs, 19 were simple, 16 were located in lower lobes, and 17 were located in the subpleural region. Furthermore, 2 of the 13 patients experienced coughing, 2 experienced dyspnea, and 1 experienced massive hemoptysis. All PAVMs were subjected to superselective TAE using a detachable balloon or coils. Six PAVMs (28.6%) in three patients (23.1%) were subsequently recanalized as determined by contrast-enhanced CT scan. All 3 patients were identified during long-term follow up (mean: 61.9 months). One of the 3 patients experienced an acute stroke due to thrombi migration in the middle cerebral artery following PAVM recanalization. Conclusion: TAE with coils is effective for the treatment of PAVMs, and it should be noted that patients who undergo embolotherapy require careful surveillance, due to the need for recanalization during follow-up.
Databáze: OpenAIRE