| Autor: |
Nayra Avina Padilla, K. Avina-Padilla, M Duarte Gutierrez, M E Miranda Flores, J. C. Rivas-Ferreira, D Rivera Marquez, M O Guerrero Valle |
| Rok vydání: |
2022 |
| Zdroj: |
International Journal of Cancer Science and Therapy. :1-5 |
| DOI: |
10.31487/j.ijcst.2022.02.01 |
| Popis: |
Mantle Cell Lymphoma (MCL) is a lymphohematopoietic cancer of follicular origin and diffuse growth. It is a rare small B-cell lymphoma, with an incidence of 7-10% of all non-Hodgkin lymphomas, affecting adults (55-60 years), of which 80% are typically male. According to the World Health Organization guidelines, the diagnosis of MCL should be established based on morphological examination and immunophenotyping with detection of cyclin D1 resulting from the chromosomal translocation t(11;14)(q13;q32) of the CCND1 gene or SOX11 protein overexpression. Herein we present an infrequent clinical case of a female patient with MCL who presented erythroderma as a paraneoplastic cutaneous disorder. Moreover, we delved into the molecular insights of immune B-cell lymphocytic affections in this communication. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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