Thermal characterization of raw material pentoxifylline using thermoanalytical techniques and Pyr-GC/MS

Autor:	Valmir Gomes de Souza, Rui Oliveira Macêdo, Fábio Santos de Souza, José Valdilânio Virgulino Procópio, Agna Hélia de Oliveira, Márcia Ferraz Pinto, Elisana Afonso de Moura
Rok vydání:	2011
Předmět:	Chromatography Materials science Analytical chemistry Raw material Condensed Matter Physics Pentoxifylline Characterization (materials science) Thermal Vaporization medicine Physical and Theoretical Chemistry Gas chromatography–mass spectrometry Thermal analysis Pyrolysis medicine.drug
Zdroj:	Journal of Thermal Analysis and Calorimetry. 106:763-766
ISSN:	1572-8943 1388-6150
Popis:	This work studied the thermal characterization of the pentoxifylline raw material through thermoanalytical techniques (TG, DSC, DSC-photovisual) and analysis of degradation products by Pyr-GC/MS. The picture obtained with DSC-photovisual showed the total vaporization of pentoxifylline at 230.0 °C. The TG dynamical curve presented only one step for the loss of mass evidencing to be a kinetic process of zero order reaction. The pyrograms obtained for pentoxifylline sample in the solid state and solution in the temperatures of 250.0, 300.0, and 400.0 °C, showed only one peak identifying the pentoxifylline.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2eaaec33b33326b0a18ee7352386c40c https://doi.org/10.1007/s10973-011-1839-4 Zobrazit plný text záznamu Plný text ve formátu PDF