Occurrence of Strains of Pneumococci Which React With More Than One Type-Specific Antipneumococcal Serum
| Autor: | Howard J. Shaughnessy, George F. Forster |
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| Rok vydání: | 1940 |
| Předmět: | |
| Zdroj: | Experimental Biology and Medicine. 44:306-309 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-44-11440p |
| Popis: | Pneumococci are commonly classed among the best examples of bacterial type-specificity. While cross-reactions frequently occur involving types 3 and 8 and less frequently other types, they have usually been considered from the standpoint of the cross-reacting antibodies that sometimes develop during immunization rather than from the standpoint of the antigenic type-multiplicity which causes them.1, 2Several strains of pneumococci that conspicuously violate the prevailing conception of type-specificity have been isolated recently in this laboratory. Neufeld tests with sera of 3 different manufacturers show that each of these strains reacts with at least 3 type-specific sera.Table I summarizes the reactions of 6 such strains. It will be noted that each strain shows somewhat greater capsular swelling with one serum (either type 29 or type 24) than with others. However, reaction is only slightly less with a second, and in some strains with a third, serum.With the exception of the Hoge strain all 6 were isolat... |
| Databáze: | OpenAIRE |
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