The skin response of rabbits to non-hemolytic streptococci
| Autor: | C. L. Derick, C. H. Andrewes |
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| Rok vydání: | 1925 |
| Předmět: | |
| Zdroj: | Experimental Biology and Medicine. 23:116-118 |
| ISSN: | 1535-3699 1535-3702 |
| Popis: | A study of the skin reactions in rabbits which were induced by intra-dermal injection of non-hemolytic streptococci demonstrated an unusual phenomenon. Following the injection of these microorganisms a local reaction took place which reached its maximum within 24 to 36 hours. The lesion then diminished until the eighth day, when an exacerbation occurred which at times approached the original lesion in intensity. This persisted for about 2 days and disappeared slowly. The late lesion is referred to as the “secondary reaction.”This reaction was first encountered while studying a green streptococcus isolated from a rheumatic subcutaneous fibroid nodule; with it definite secondary reactions were induced in 50 per cent of normal adult rabbits and doubtful reactions in an additional 13 per cent. On further extending the strains of green streptococci studied, the reaction was found to be incited by 5 out of 10 strains from nodules, blood or heart of rheumatic fever patients; by 1 out of 4 strains from the blood ... |
| Databáze: | OpenAIRE |
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