Design of a hybrid nanostructure based on fullerene C60 and biologically active substance for modeling physiological properties of compounds

Autor: V. L. Zamoiskii, A. V. Smolina, N. A. Markova, Vladimir V. Grigoriev, Gjumrakch Aliev, D. V. Mishchenko, R. A. Kotel’nikova, D. A. Poletaeva, Sergey O. Bachurin, V. S. Romanova, G. I. Van'kin, Alexander I. Kotelnikov, I. I. Faingold
Rok vydání: 2014
Předmět:
Zdroj: Russian Chemical Bulletin. 63:2375-2382
ISSN: 1573-9171
1066-5285
DOI: 10.1007/s11172-014-0750-0
Popis: The effects of cognitive-stimulating substance BD-2 of the γ-carboline family and a hybrid compound based on fullerene C60 and attached BD-2 on various aspects of the behavior of animals were studied. The synthesized hybrid fullerene compound (HFC) has no side psychostimulating effect characteristic of BD-2 but fully retains the properties of a cognitive-stimulating agent. The design of hybrid compounds based on fullerene C60 and pharmacologically active groups can be one of the ways for optimizing therapeutically promising compounds.
Databáze: OpenAIRE
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