Syndecan-4 forces integrins to cooperate
| Autor: | Christophe Guilluy, Monika E. Dolega |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
biology
Chemistry Mechanical Engineering Integrin 02 engineering and technology General Chemistry Adhesion Matrix (biology) 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics 01 natural sciences 0104 chemical sciences Syndecan 1 Cell biology Mechanics of Materials biology.protein General Materials Science Cell response 0210 nano-technology Cell adhesion Receptor |
| Zdroj: | Nature Materials. 19:587-588 |
| ISSN: | 1476-4660 1476-1122 |
| DOI: | 10.1038/s41563-020-0689-5 |
| Popis: | While integrin-based adhesions are thought to underlie many aspects of cell response to localized tension, another matrix receptor, syndecan-4, has now been shown to act as a mechanosensor, which triggers cell-wide integrin activation and adhesion reinforcement. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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