Spitz Nevus (case study)
| Autor: | A. O. Kostiukov, O. G. Kostiuk, S. V. Vernygorodskyi, K. V. Gumenyuk, L. V. Fomina |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Reports of Vinnytsia National Medical University. 26:72-76 |
| ISSN: | 2522-9354 1817-7883 |
| DOI: | 10.31393/reports-vnmedical-2022-26(1)-13 |
| Popis: | Annotation. Spitz nevus is a difficult issue in the diagnosis of skin tumors and in the clinical tactics of management of patients with this disorder. The case of diagnosis of Spitz's nevus in patient R., born in 1978 is given. in which a dermatologist's examination revealed skin tumors on the torso and extremities. Spitz's nevus was suspected. Dermatological status: on the skin of the face, neck, torso and extremities there are spots and papules, up to 6 mm (number 62) maximum, light and dark brown, without signs of inflammation, irritation and trauma. Dermatoscopic picture of pigment formations is represented by melanocyte, non-melanocyte and halo nevi. On the skin of the left breast there is a melanocyte formation asymmetric in shape in the horizontal axis, dermatoscopically corresponding to the Spitz nevus (dark brown unstructured area in the center, illuminated to the periphery with large brown granules and dots located on the periphery of the focus in the form of rays 3.8. A biopsy was performed. Histologically, there is skin with acanthosis and minor hyperortokeratosis, located in the basal layer of symmetrical, well-defined formation with refractive artifacts. The tumor is formed by vertically placed junctional nests of mainly spindle-shaped, as well as epithelioid multinucleated melanocytes with eosinophilic cytoplasm, moderate polymorphism of vesicular nuclei. The latter have numerous prominent small basophilic nucleoli. Mitotic figures and pegetoid growth are absent. Perivascular lymphocytic infiltrates are present in the papillary layer of the dermis. The patient was diagnosed with Nevis Spitz. It is recommended to monitor dynamically with dermatoscopy once a year, to avoid hyperinsolation, the use of sunscreen with SPF factor. The problem of diagnostic and treatment tactics of a patient with Spitz's nevus remains a difficult problem today. Further study of the peculiarities of Spitz's nevus in adulthood seems promising. |
| Databáze: | OpenAIRE |
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