Ceramide, a mediator of apoptosis, synergizes with paclitaxel to induce regression of the L3.6 human pancreatic carcinoma implanted in SCID mice

Autor:	Harold J. Wanebo, D. Essis, Shashikant Mehta, David Shrayer
Rok vydání:	2004
Předmět:	Cancer Research medicine.medical_specialty Ceramide business.industry Metabolite Sphingolipid chemistry.chemical_compound Endocrinology Mediator Oncology Paclitaxel chemistry Apoptosis Internal medicine medicine Cancer research Pancreatic carcinoma Cytotoxicity business
Zdroj:	Journal of Clinical Oncology. 22:2135-2135
ISSN:	1527-7755 0732-183X
DOI:	10.1200/jco.2004.22.90140.2135
Popis:	2135 Background: Ceramide, a sphingolipid metabolite, is an active signal for apoptosis. Our group has shown that it amplifies cytotoxicity induced by Paclitaxel (Taxol) and other chemotherapeutic ...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2e60c5b5b1b13531e5a552f6ba43836a https://doi.org/10.1200/jco.2004.22.90140.2135 Zobrazit plný text záznamu