Defect-free graphene enhances enzyme delivery to fibroblasts derived from patients with lysosomal storage disorders
| Autor: | Yingxian Chen, Tooba Taufiq, Niting Zeng, Neus Lozano, Angeliki Karakasidi, Heather Church, Ana Jovanovic, Simon A. Jones, Adyasha Panigrahi, Igor Larrosa, Kostas Kostarelos, Cinzia Casiraghi, Sandra Vranic |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Nanoscale. |
| ISSN: | 2040-3372 2040-3364 |
| Popis: | Biocompatible cationic graphene flakes efficiently complex and deliver the enzyme to the lysosomes of the fibroblasts derived from the patients with Mucopolysaccharidosis VI, leading to enhanced degradation of the accumulated lysosomal substrate. |
| Databáze: | OpenAIRE |
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