Synthesis, Crystal Structure, and DNA-Binding Studies of Transition Metal Complexes with 2′-(4-Dimethylaminobenzylidene)-2-hydroxybenzoylhydrazide

Autor:	Liu-Jie Wang, Heng-Xin Li, Hui-Lin Guo, Shui-Yang He, Feng-Ying Chen
Rok vydání:	2012
Předmět:	Inorganic Chemistry chemistry.chemical_compound Crystallography Ultraviolet visible spectroscopy chemistry Transition metal Elemental analysis Titration Crystal structure Physical and Theoretical Chemistry Absorption (chemistry) Fluorescence DNA
Zdroj:	Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry. 42:843-849
ISSN:	1553-3182 1553-3174
DOI:	10.1080/15533174.2011.618479
Popis:	A series of transition metal complexes of the general formula M(HL)2 (where H2L=2′-(4-dimethylaminobenzylidene)-2-hydroxybenzoylhydrazide, M=Ni, Cu, Zn, Cd) were prepared and characterized by elemental analysis, spectroscopic (IR, UV–vis) and the Ni(HL)2 was structurally characterized by X-ray crystallography. Single-crystal X-ray diffraction results suggest that Ni(II) central atom situated in a distorted square planar geometry is four-coordinated. The DNA-binding properties of these complexes with calf thymus DNA were also investigated by electronic absorption titration (UV spectroscopy) and fluorescence emission titration. The results showed that these complexes bind to DNA mainly via intercalative mode.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2e58e349dfee8441edcc4fb9a3c3c9ec https://doi.org/10.1080/15533174.2011.618479 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.