Flow cytometry applications for the analysis of chemokine receptor expression and function
| Autor: | Cristina Mazzon, Gerard J. Graham, Elena Monica Borroni, Achille Anselmo, Raffaella Bonecchi, Massimo Locati |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
0303 health sciences
Leukocyte migration Chemokine Histology medicine.diagnostic_test biology Cell Biology Pathology and Forensic Medicine Flow cytometry Cell biology 03 medical and health sciences Specific antibody Chemokine receptor 0302 clinical medicine medicine biology.protein Antibody Function (biology) Intracellular 030304 developmental biology 030215 immunology |
| Zdroj: | Cytometry Part A. 85:292-301 |
| ISSN: | 1552-4922 |
| DOI: | 10.1002/cyto.a.22439 |
| Popis: | Chemokine receptors play an important role in leukocyte migration, both in physiological and pathological conditions, and the interest in new methodologies for their detection is increasing. In this review, we focused on chemokine receptors detection through flow cytometric approaches, including the use of specific antibodies and fluorescent chemokines, and on approaches aimed at the analysis of their functions, from intracellular trafficking to signaling activities. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text