| Autor: |
Laura Foulgoc, André Guingant, Doumadé Zon, Romy Vomiandry, Drissa Sissouma, Mathilde Pantin, Sylvain Collet |
| Rok vydání: |
2015 |
| Předmět: |
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| Zdroj: |
Tetrahedron Letters. 56:2110-2112 |
| ISSN: |
0040-4039 |
| DOI: |
10.1016/j.tetlet.2015.03.010 |
| Popis: |
The total synthesis of racemic γ-indomycinone has been achieved following an innovating convergent approach. The key step in the construction of the tetracyclic core corresponds to a Diels–Alder reaction between a substituted 5-isoprenyl-3,4-dihydro-2H-pyran and juglone as the dienophile. The used strategy can easily be transposed to the synthesis of (R)-γ-indomycinone starting from optically pure (2R)-2-benzyloxy-2-methylbutanal. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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