Pilot study of a multimodal intervention to enhance sexual function in survivors of hematopoietic stem cell transplantation
| Autor: | Meredith Saylor, Areej El-Jawahri, Zhigang Li, Joseph A. Greer, Chrisa Hunnewell, Yi Bin Chen, Nicole Pensak, Jennifer S. Temel, Sarah Fishman, Lauren Waldman, Netana Markovitz, Elyse R. Park, Jessica Driscoll, Thomas R. Spitzer, Don S. Dizon, Lara Traeger, Julie Vanderklish, Steven L. McAfee |
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| Rok vydání: | 2018 |
| Předmět: |
Cancer Research
medicine.medical_specialty medicine.biofluid business.industry Vaginal lubrication media_common.quotation_subject Orgasm Hospital Anxiety and Depression Scale 03 medical and health sciences Distress 0302 clinical medicine Sexual dysfunction Mood Oncology Quality of life 030220 oncology & carcinogenesis Internal medicine Medicine medicine.symptom Sexual function business 030215 immunology media_common |
| Zdroj: | Cancer. 124:2438-2446 |
| ISSN: | 0008-543X |
| Popis: | BACKGROUND Although sexual dysfunction is common after hematopoietic stem cell transplantation (HCT), interventions to address sexual function are lacking. METHODS We conducted a pilot study to assess the feasibility and preliminary efficacy of a multimodal intervention to address sexual dysfunction in allogeneic HCT survivors. Transplant clinicians screened HCT survivors ≥3 months post-HCT for sexual dysfunction causing distress. Those who screened positive attended monthly visits with a trained transplant clinician who: 1) performed an assessment of the causes of sexual dysfunction; 2) educated and empowered the patient to address his or her sexual concerns; and 3) implemented therapeutic interventions targeting the patient's needs. Feasibility was defined as having approximately 75% of patients who screened positive agreeing to participate and 80% attending at least 2 intervention visits. We administered the Patient-Reported Outcomes Measurement Information System (PROMIS) sexual function and satisfaction measure, the Functional Assessment of Cancer Therapy-Bone Marrow Transplant (FACT-BMT), and the Hospital Anxiety and Depression Scale (HADS) to evaluate sexual function, quality of life (QOL), and mood, respectively, at baseline and 6 months postintervention. RESULTS Approximately 33.1% of patients (50 of 151 patients) screened positive for sexual dysfunction causing distress and 94.0% (47 of 50 patients) agreed to participate, with 100% attending 2 intervention visits. Participants reported improvements in satisfaction (P |
| Databáze: | OpenAIRE |
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