Autor: |
Jesús Herreros, Silvia Carnicero, Javier Enjuto, María Francisca Garijo, José Fernando Val-Bernal |
Rok vydání: |
2012 |
Předmět: |
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Zdroj: |
Revista Española de Patología. 45:175-180 |
ISSN: |
1699-8855 |
DOI: |
10.1016/j.patol.2011.11.004 |
Popis: |
Isolated (idiopathic) aortitis is a rare process characterized by giant cells or lymphoplasmacytic inflammation of the aorta and is an uncommon cause of ascending aortic aneurismal disease. Isolated aortitis usually manifests as an aneurysm of the ascending aorta and it is often an incidental finding during the histopathological study of the aortic wall after thoracic surgery. We present two cases of isolated active aortitis discovered on microscopy of surgically excised aneurismal tissue. The patients were 63- and 62-year-old females, both hypertensive, one a heavy smoker but neither of whom had a history of rheumatic disease. Isolated aortitis occurred in 2% of surgical interventions for ascending aneurysms. Isolated aortitis with giant cells in the absence of previously established giant cell (temporal) arteritis is difficult to identify. Cases showing aortitis with giant cells only in the histopathologic study are usually not a manifestation of giant cell (temporal) arteritis. Since incidentally discovered aortitis may represent a focal lesion that has been surgically removed, a conservative approach to the management of these patients, which should include careful periodical evaluation, is recommended. All surgical aortic samples should be submitted for histopathological examination. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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