Synthesis of some new imidazo[1,2-a]pyrimidin-5(1H)-ones as potential antineoplastic agents

Autor:	El-Sayed A. M. Badawey, Thomas Kappe
Rok vydání:	1995
Předmět:	Diethyl ethoxymethylenemalonate chemistry.chemical_compound Chemistry Organic Chemistry Organic chemistry Sulfate In vitro
Zdroj:	Journal of Heterocyclic Chemistry. 32:1003-1006
ISSN:	1943-5193 0022-152X
DOI:	10.1002/jhet.5570320355
Popis:	Some substituted imidazo[1,2-a]pyrimidin-5(1H)-ones have been synthesized via the reaction of 2-aminoimidazole sulfate with some β-keto esters, diethyl ethoxymethylenemalonate and ethyl ethoxymethylenecyanoacetate. Several compounds were screened for their in vitro antineoplastic and anti-HIV activity but were inactive.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2e1d568b6d168b6a7cd3bb6a6017d36a https://doi.org/10.1002/jhet.5570320355 Zobrazit plný text záznamu Plný text