Smoking Is Associated with Sex-Specific Effects on Bone Microstructure in Older Men and Women
| Autor: | Marcella D. Walker, Mariana Bucovsky, Sanchita Agarwal, Ivelisse Colon, Carmen Germosen, John C. Williams, Nayoung Kil, Natalie E. Cusano |
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| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty medicine.diagnostic_test business.industry Endocrinology Diabetes and Metabolism High resolution 030209 endocrinology & metabolism Mean age Sex specific Mixed race 03 medical and health sciences 0302 clinical medicine Trabecular bone score Internal medicine medicine Musculoskeletal health Radiology Nuclear Medicine and imaging Orthopedics and Sports Medicine 030101 anatomy & morphology Risk factor Quantitative computed tomography business |
| Zdroj: | Journal of Clinical Densitometry. 24:341-350 |
| ISSN: | 1094-6950 |
| DOI: | 10.1016/j.jocd.2020.07.002 |
| Popis: | Background: Smoking is a risk factor for fracture, but the mechanism by which smoking increases fracture risk is unclear. Methods: Musculoskeletal health was compared with dual energy X-ray absorptiometry (DXA), high resolution peripheral quantitative computed tomography (HR-pQCT), trabecular bone score, and vertebral fracture assessment in current and past smokers and nonsmokers from a multiethnic study of adults ≥ age 65. Skeletal indices were adjusted for age and weight. Results: Participants (n = 311) were mean age (±SD) 76.1 ± 6.5 years, mostly female (66.0%) and non-white (32.7% black/39.4% mixed race/26.3% white). Mean pack-years was 34.6 ± 20.4. In men (n = 106), weight and BMI were lower (both p |
| Databáze: | OpenAIRE |
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