Degradation of nucleic acids and nucleotides in several conditions with perspectives of retrieval: A review

Autor:	Agustina Ortiz Soriano, José Martínez Reyes, Melitón Estrada Jaramillo, Lenin Ejecatl Medina Orozco, Iván Vera Romero
Rok vydání:	2014
Předmět:	chemistry.chemical_classification chemistry.chemical_compound Biochemistry chemistry Oligonucleotide Radical Biomolecule Deamination Nucleic acid Nucleotide General Medicine Chemical decomposition DNA
Zdroj:	Advances in Bioscience and Biotechnology. :36-39
ISSN:	2156-8502 2156-8456
DOI:	10.4236/abb.2014.51006
Popis:	Deoxyribonucleic acid (DNA) or oligonucleotides, can be modified in several ways as chemical degradation by electrophilic reaction, attack of radicals, hydrolytic deamination or oxidative damage caused by ionizing radiation. This work discussed these degradation mechanisms, determining the effects on these biomolecules. The actual knowledge about DNA damages only permits partial enzymatic repair treatments.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2e11b7164c6f49b51038cca5a5e322b4 https://doi.org/10.4236/abb.2014.51006 Zobrazit plný text záznamu