Facile approaches toward the synthesis of 6H-isoindolo[2,1-α]indol-6-ones via palladium-catalyzed carbonylation with carbon monoxide
Autor: | Shen Lin, Qiufeng Huang, Qingshuai Han, Xiaofeng Zhang, Shurong Fu |
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Rok vydání: | 2016 |
Předmět: |
010405 organic chemistry
Chemistry Organic Chemistry Intermolecular force chemistry.chemical_element 010402 general chemistry 01 natural sciences Biochemistry 0104 chemical sciences Catalysis chemistry.chemical_compound Iodobenzenes Intramolecular force Drug Discovery Organic chemistry Carbonylation Palladium Carbon monoxide |
Zdroj: | Tetrahedron Letters. 57:4165-4169 |
ISSN: | 0040-4039 |
Popis: | Two facile methods for the preparation of 6 H -isoindolo[2,1-α]indol-6-ones were developed. In the first protocol, 6 H -isoindolo[2,1-α]indol-6-ones were prepared from 2-(2-iodophenyl)-1 H -indoles via palladium-catalyzed intramolecular aminocarbonylation. The second involves intermolecular carbonylation of indoles with iodobenzenes followed by intramolecular cross-dehydrogenative-coupling. |
Databáze: | OpenAIRE |
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