Facile approaches toward the synthesis of 6H-isoindolo[2,1-α]indol-6-ones via palladium-catalyzed carbonylation with carbon monoxide

Autor: Shen Lin, Qiufeng Huang, Qingshuai Han, Xiaofeng Zhang, Shurong Fu
Rok vydání: 2016
Předmět:
Zdroj: Tetrahedron Letters. 57:4165-4169
ISSN: 0040-4039
Popis: Two facile methods for the preparation of 6 H -isoindolo[2,1-α]indol-6-ones were developed. In the first protocol, 6 H -isoindolo[2,1-α]indol-6-ones were prepared from 2-(2-iodophenyl)-1 H -indoles via palladium-catalyzed intramolecular aminocarbonylation. The second involves intermolecular carbonylation of indoles with iodobenzenes followed by intramolecular cross-dehydrogenative-coupling.
Databáze: OpenAIRE