Perfluorobenzene derivatives as derivatising agents for the gas chromatography of primary and secondary amines using electron capture detection
| Autor: | A.C. Moffat, S.B. Matin, Malcolm Rowland, E.C. Horning |
|---|---|
| Rok vydání: | 1972 |
| Předmět: |
chemistry.chemical_classification
Phenethylamine Primary (chemistry) Chromatography Double bond Electron capture Organic Chemistry chemistry.chemical_element General Medicine Ring (chemistry) Biochemistry Nitrogen Analytical Chemistry Electron capture detector chemistry.chemical_compound chemistry Organic chemistry Gas chromatography |
| Zdroj: | Journal of Chromatography A. 66:255-260 |
| ISSN: | 0021-9673 |
| DOI: | 10.1016/s0021-9673(01)82288-3 |
| Popis: | A variety of perfluorobenzene derivatives of phenethylamine and N-methyl-phenethylamine were prepared and examined by gas chromatography using an electron capture detector and by gas chromatographic-mass spectrometric techniques. The structural requirement for good electron capturing properties was found to be the presence of a double bond between nitrogen or oxygen and the carbon atom adjacent to the perfluoroaromatic ring. The best derivatising agent for secondary amines was pentafluorobenzoyl chloride; for primary amines the choice was between pentafluorobenzaldehyde and pentafluorobenzoyl chloride. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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