Protective effect of butanol extracts of skin of Anguilla japonica against endoplasmic reticulum stress-induced insulin resistance via the AMPK pathway in L6 myotubes
| Autor: | MinKyun Na, Ju Hye Yang, Geum Jin Kim, Cheorl-Ho Kim, Young-Chae Chang, Fansi Jin, Yong-Tae Jeong, Dong-Soo Kim, Xian Li, Hyeun Wook Chang, Seung-Lark Hwang |
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| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
biology Chemistry Kinase Endoplasmic reticulum Glucose uptake AMPK medicine.disease Applied Microbiology and Biotechnology Insulin resistance Endocrinology AMP-activated protein kinase Internal medicine Unfolded protein response medicine biology.protein Protein kinase A Food Science Biotechnology |
| Zdroj: | Food Science and Biotechnology. 24:1069-1075 |
| ISSN: | 2092-6456 1226-7708 |
| Popis: | The effect of butanol extracts of the skin of Anguilla japonica (BESA) on endoplasmic reticulum (ER) stress-induced insulin resistance in L6 myotubes was investigated. Western blotting revealed that BESA increased phosphorylation of AMP-activated protein kinase (AMPK) and acetyl-CoA carboxylase, and stimulated glucose uptake in L6 myotubes. Stimulation of AMPK and glucose uptake by BESA were significantly (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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