| Autor: |
Takatsugu Murata, Hisazumi Tsutsui, Takumi Yoshida, Hirokazu Kubota, Shintaro Hiraishi, Hiyo Natsukawa, Yuki Suzuki, Daiki Hiraga, Takahiro Mori, Yutaro Maekawa, Satoru Tateyama, Kiyotaka Toyoyama, Keiichi Ito, Kyohei Suzuki, Keita Yonekura, Natsumi Shibata, Teruyuki Sato, Yasutaka Tasaki, Takehiko Inohana, Atsuhiro Takano, Isamu Shiina |
| Rok vydání: |
2022 |
| DOI: |
10.26434/chemrxiv-2022-p8hxs |
| Popis: |
The first total synthesis of (+)-tanzawaic acid B, a natural polyketide bearing a pentadienoic ester and octalin moiety, has been accomplished. The synthetic improvement from previous synthetic conditions facilitated our gram-scale synthesis of the chiral octalin that possesses seven stereogenic centers and that is the core skeleton of almost all of the tanzawaic acid family. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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