Successful Combination Chemotherapy for Metastatic Parathyroid Carcinoma
| Autor: | Caldwell Esselstyn, James R. Cunningham, Ronald M. Bukowski, Leslie R. Sheeler |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
medicine.medical_specialty
Chemotherapy Cyclophosphamide Metastatic Parathyroid Carcinoma business.industry Dacarbazine medicine.medical_treatment Combination chemotherapy Gastroenterology Surgery Refractory Fluorouracil Internal medicine Internal Medicine medicine business medicine.drug Imidazole carboxamide |
| Zdroj: | Archives of Internal Medicine. 144:399 |
| ISSN: | 0003-9926 |
| DOI: | 10.1001/archinte.1984.00350140229032 |
| Popis: | • A 54-year-old patient with metastatic parathyroid carcinoma and severe hypercalcemia refractory to conventional treatment was treated with chemotherapy consisting of fluorouracil, 500 mg/sq m intravenously (IV) daily for four days (24-hour infusion), cyclophosphamide, 500 mg/sq m IV daily for four days, and dacarbazine (imidazole carboxamide), 200 mg/sq m IV daily for four days. Complete objective and partial biochemical responses were noted, with the response duration being 5.0+ months. The toxic reaction was moderate and predominantly gastrointestinal. (Arch Intern Med1984;144:399-400) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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