Case report Tamoxifen for retroperitoneal fibrosis
| Autor: | J C Chambers, K McGovern |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Pathology
medicine.medical_specialty business.industry Renal function General Medicine Retroperitoneal fibrosis Collagen fibril 03 medical and health sciences 0302 clinical medicine Anesthesiology and Pain Medicine Lymphatic system 030502 gerontology Retroperitoneal structures 030220 oncology & carcinogenesis medicine medicine.symptom 0305 other medical science business Tamoxifen medicine.drug |
| Zdroj: | Palliative Medicine. 19:163-164 |
| ISSN: | 1477-030X 0269-2163 |
| DOI: | 10.1191/0269216305pm982cr |
| Popis: | Retroperitoneal fibrosis is characterised by diffuse inflammatory proliferation of fibroblasts and the deposition of collagen fibrils throughout the retroperitoneum, especially in perivascular sites. This results in blockage of the ureters and other tubular retroperitoneal structures such as the vasculature and lymphatic channels. Left untreated, it typically follows a progressive and fatal course. The condition responds favourably to tamoxifen and several case reports describe an improvement in renal function on this therapy. This case report describes a subjective and objective functional improvement of lymphoedema secondary to retroperitoneal fibrosis with the use of tamoxifen. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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