The Incidence of Coronary Artery Abnormality in Incomplete Kawasaki Disease
| Autor: | Hiroshi Yanagawa, Yoshio Imada, Yosikazu Nakamura, Tomoyoshi Sonobe, Seijiro Aso, Keiji Tsuchiya |
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| Rok vydání: | 2003 |
| Předmět: | |
| Zdroj: | Pediatric Research. 53:164-164 |
| ISSN: | 1530-0447 0031-3998 |
| Popis: | Purpose: To clarify the incidence of coronary artery abnormality (CAA) among incomplete (atypical) Kawasaki disease.Method: We defined incomplete cases as follows. The incomplete Kawasaki disease of narrow definition (nd-IKD) consists of cases with 4 items of principal symptoms without CAA, and cases with less than 4 items of principal symptoms regardless of CAA. The broad definition of incomplete Kawasaki disease (bd-IKD) consists of cases with less than 5 items of principal symptoms regardless of CAA. About 48,000 cases of Japanese nationwide Kawasaki disease survey were analyzed using our criteria. The proportion, age distribution and the incidence of CAA of incomplete cases were compared with that of typical cases with 5 to 6 items of principal symptoms. Result: The proportion of typical cases, bd-IKD and nd-IKD were 85.0%, 15.0% and 11.5%, respectively. The frequency of incomplete cases was slightly higher among the age groups of less than 1 year and over 5 year. The incidence of acute phase CAA among typical cases, bd-IKD and nd-IKD were 19%, 20% and 5%, respectively. The incidence of CAA of 30th illness day among typical cases, bd-IKD and nd-IKD were 12%, 11% and 2%, respectively. Discussion: Although the proportion of CAA in nd-IKD was smaller than that of typical cases, the proportion of CAA in bd-IKD was almost same as that of typical cases. Therefore the same treatment is required for the cases with less than 5 items of principal symptoms. The revision of diagnostic guideline may be necessary when the above mentioned evidence is confirmed by precise secondary survey. |
| Databáze: | OpenAIRE |
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