297 Long-term metabolic and endocrine activity changes in response to clenbuterol in mature female pigs

Autor:	B. Vinković, Tihomira Gojmerac, B. Mandić, M. Koršić, A. Tomašić
Rok vydání:	2003
Předmět:	chemistry.chemical_classification medicine.medical_specialty Serum insulin Fatty acid General Medicine Metabolism Biology Toxicology Endocrinology chemistry Clenbuterol Internal medicine medicine Endocrine system Receptor medicine.drug
Zdroj:	Toxicology Letters. 144:s82
ISSN:	0378-4274
DOI:	10.1016/s0378-4274(03)90296-7
Popis:	In present study, the effect of intravenously repeated administration of clenbuterol in a growth-promotiong dose on the metabolic and endocrine status of mature female pigs was evaluated on the basis of biochemical findings.Serum 17beta-estradiol and progesterone concentrantion and serum insulin, nonesterified fatty acid and glucose concentration were measured after long-term administration of clenbuterol to mature female pigs.On the basis of the data obtained, we suggest that long-term administration of clenbuterol in growth-promoting dose to female pigs provoked only subtle metabolic and endocrine activity changes, indicating down-regulation of the specific beta2-adrenergic receptors in target tissues.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2dd1b226c67dacbf5b0a3f1d7b297c6d https://doi.org/10.1016/s0378-4274(03)90296-7 Zobrazit plný text záznamu Full Text from ScienceDirect