Preparation of cation-exchange sorbent for 99mTc generator chromatographic column

Autor:	N. S. Il’icheva, N. K. Kitaeva, V. R. Duflot
Rok vydání:	2011
Předmět:	Pharmacology Sorbent Chromatography Elution Polyacrylic acid chemistry.chemical_element Manganese Polyethylene Grafting chemistry.chemical_compound Adsorption chemistry Yield (chemistry) Drug Discovery
Zdroj:	Pharmaceutical Chemistry Journal. 45:363-365
ISSN:	1573-9031 0091-150X
Popis:	A new cation-exchange sorbent based on polyethylene powder modified by polyacrylic acid was prepared for a technetium-99 m generator column. The dependence of the kinetics of polyethylene modification on the composition of the grafting solution was studied. The adsorption of manganese ions by the obtained sorbent has been studied. The new sorbent was tested in a technetium-99 m generator column with the maximum output activity. It is expedient to use the sorbent in a technetium-99 m generator column in order to improve the quality of the effluent, increase the consistency of the yield of pertechnetate ions, and maintain the eluate medium in a condition close to neutral.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2dca47239479df8a16b86bc029db74f4 https://doi.org/10.1007/s11094-011-0634-7 Zobrazit plný text záznamu Plný text ve formátu PDF