Elevation of myocardial creatine kinase in absence of myocardial injury (Case report with literature review)
| Autor: | Chady Sarraf, Yaser Elnahar, Joseph Daoko, Fayez Shamoon, Karim El Kersh, Jennifer C. Kam |
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| Rok vydání: | 2011 |
| Předmět: |
Myocardial Creatine Kinase
medicine.medical_specialty High molecular mass Myocardial ischemia biology business.industry Ischemia nutritional and metabolic diseases social sciences medicine.disease digestive system Isozyme Muscle enzyme stomatognathic diseases Internal medicine Unnecessary Procedure biology.protein Cardiology medicine Creatine kinase business health care economics and organizations |
| Zdroj: | Journal of Clinical Medicine and Research. 3:89-91 |
| ISSN: | 2141-2235 |
| Popis: | Macro enzymes are high molecular mass complexes that consist of normal serum enzymes and protein-immunoglobulins. Creatine kinase (CK) is a muscle enzyme that has three isoenzymes. Two types of macro CK have been described; Macro CK type 1 and macro CK type 2. We report a case where cardiac enzymes were persistently elevated in the absence of myocardial injury. The false elevation was secondary to the presence of macro CK type 1 yielding aberrantly increased CK-MB. Our patient lacked clinical as well as electrocardiographic (EKG) changes to validate myocardial ischemia. Apperception of diagnosing falsely elevated cardiac markers is imperative to avoid unnecessary procedures Key words: Macro CK, ischemia, myocardial infraction. |
| Databáze: | OpenAIRE |
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